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KMID : 1103720150720020083
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Journal of the Korean Society of Radiology
2015 Volume.72 No. 2 p.83 ~ p.91
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The Effect of Low-Dose β-Blocker on Heart Rate and Heart Rate Variability in Healthy Subjects with a Resting Heart Rate of Less than 65 Beats per Minute: Effect on the Image Quality of Prospective Electrocardiography-Gated Coronary CT Angiography
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Park Chul-Hwan
Lee Sang-Min
Hong Yoo-Jin
Kim Tae-Hoon
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Abstract
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Purpose : We assessed the effect of a low-dose β-blocker on heart rate (HR), HR variability (HRV) and image quality of prospective electrocardiography-gated coronary CT angiography (CCTA) in healthy subjects with low HR.
Materials and Methods : CCTA was performed with a 64-slice CT in 75 subjects with a HR of less than 65 beats per minute (bpm). Subjects were divided into 2 groups: Group 1 (G1), 35 with a low dose β-blocker; and Group 2 (G2), 40 without pre-medication. The image quality (IQ) of the CCTA was assessed on a 4-point grading scale (1, poor; 4, excellent).
Results : Initial HR (bpm) was not different between the 2 groups. HR during CCTA was lower in G1 than G2 (50.3 ± 5.6 vs. 53.3 ± 4.8, p = 0.016). HRV was not different between the 2 groups. Per-segment analysis showed better IQ at the mid-segment
Conclusion : Low-dose β-blocker reduced HR and improved the IQ of CCTA in a few segments, even at a HR of less than 65 bpm. However the effect was limited.
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KEYWORD
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Coronary CT Angiography, Heart Rate, Heart Rate Variability, β-Blocker, Image Quality
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